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Cat. Number
286769404856766
Chemical Name
AGK 2
CAS Number
[304896-28-4]
Mol. Formula
C23H13Cl2N3O2
Mol. Weight
434.27
Qty 1
10mg
Qty 2
50mg
Synonym
2-Cyano-3-[[5-(2,5-dichlorophenyl)- 2-furanyl]-N-5-quinolinyl-2-propenamide
Solubility
Soluble to 10 mM in DMSO
Storage condition
Store at +4°C
References
Selective inhibitor of SIRT2 (IC50 = 3.5 μM). Displays no activity at SIRT1 and SIRT3 at concentrations up to 40 μM. Reduces α-synuclein-mediated toxicity in in vitro and in vivo models of Parkinson's disease.
Purity: >98 %
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