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/ Products Classification 点击展开+Cat. Number | 286769404856766 |
Chemical Name | AGK 2 |
CAS Number | [304896-28-4] |
Mol. Formula | C23H13Cl2N3O2 |
Mol. Weight | 434.27 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 2-Cyano-3-[[5-(2,5-dichlorophenyl)- 2-furanyl]-N-5-quinolinyl-2-propenamide |
Solubility | Soluble to 10 mM in DMSO |
Storage condition | Store at +4°C |
References | Selective inhibitor of SIRT2 (IC50 = 3.5 μM). Displays no activity at SIRT1 and SIRT3 at concentrations up to 40 μM. Reduces α-synuclein-mediated toxicity in in vitro and in vivo models of Parkinson's disease. Purity: >98 % |
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