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Cat. Number
286750176277847
Chemical Name
AG 99
CAS Number
[122520-85-8]
Mol. Formula
C10H8N2O3
Mol. Weight
204.18
Qty 1
10mg
Qty 2
50mg
Synonym
(E)-2-Cyano-3-(3,4-dihydroxyphenyl) -2-propenamide
Solubility
Soluble to 5 mM in ethanol and to 100 mM in DMSO
Storage condition
Desiccate at +4°C
References
Epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 10 μM) that is selective over insulin receptor kinase. Blocks tyrosine phosphorylation of p145met and promotes cell death of normal and cancer cells via activation of caspase-like proteases in vitro.
Purity: >99 %
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