服务热线
021-60498804
产品中心
/ Products Classification 点击展开+Cat. Number | 286750176277847 |
Chemical Name | AG 99 |
CAS Number | [122520-85-8] |
Mol. Formula | C10H8N2O3 |
Mol. Weight | 204.18 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | (E)-2-Cyano-3-(3,4-dihydroxyphenyl) -2-propenamide |
Solubility | Soluble to 5 mM in ethanol and to 100 mM in DMSO |
Storage condition | Desiccate at +4°C |
References | Epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 10 μM) that is selective over insulin receptor kinase. Blocks tyrosine phosphorylation of p145met and promotes cell death of normal and cancer cells via activation of caspase-like proteases in vitro. Purity: >99 % |