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Cat. Number
286743748709198
Chemical Name
AG 879
CAS Number
[148741-30-4]
Mol. Formula
C18H24N2OS
Mol. Weight
316.46
Qty 1
10mg
Synonym
(2E)-3-[3,5-Bis(1,1-dimethylethyl)- 4-hydroxyphenyl]-2-cyano-2-propenethioamide
Solubility
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Storage condition
Store at -20°C
References
Inhibitor of the tyrosine kinase activity of nerve growth factor (NGF) TrkA. Decreases cellular proliferation in human muscular sarcoma cell lines. Also inhibits ErbB2 and VEGFR-2 (IC50 values are approximately 1 μM for both).
Purity: >99 %
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