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| Cat. Number | 286691413098864 |
| Chemical Name | AG 490 |
| CAS Number | [133550-30-8] |
| Mol. Formula | C17H14N2O3 |
| Mol. Weight | 294.31 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | (E)-2-Cyano-3-(3,4-dihydrophenyl)-N -(phenylmethyl)-2-propenamide |
| Solubility | Soluble to 20 mM in ethanol and to 100 mM in DMSO |
| Storage condition | Store at RT |
| References | Selective inhibitor of EGF receptor tyrosine kinase (IC50 values are 2 and 13.5 μM for EGFR and ErbB2 respectively). Inhibitor of JAK2, JAK3/STAT, JAK3/AP-1 and JAK3/MAPK pathways and potently inhibits cytokine-independent cell growth in vitro and tumor cell invasion in vivo. Purity: >99 % |
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