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| Cat. Number | 286684384819204 |
| Chemical Name | AG 213 |
| CAS Number | [122520-86-9] |
| Mol. Formula | C10H8N2O2S |
| Mol. Weight | 220.25 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | (E)-2-Cyano-3-(3,4-dihydroxyphenyl) -2-propenthioamide |
| Solubility | Soluble to 25 mM in ethanol and to 100 mM in DMSO |
| Storage condition | Desiccate at +4°C |
| References | Epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor (PDGFR) kinase inhibitor (IC50 values are 2.4 and 3 μM respectively). Stimulates microtubule polymerization and promotes neurite outgrowth > 17-fold over basal conditions in vitro. Also weakly inhibits protein kinase C (IC50 = 60 μM). |
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