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/ Products Classification 点击展开+Cat. Number | 286269822106600 |
Chemical Name | Valproic acid, sodium salt |
CAS Number | [1069-66-5] |
Mol. Formula | C8H15NaO2 |
Mol. Weight | 166.19 |
Qty 1 |
100mg |
Synonym | Sodium 2-propylpentanoate |
Solubility | Soluble to 100 mM in water |
Storage condition | Desiccate at RT |
References | Histone deacetylase inhibitor (IC50 = 400 μM) that exhibits anticancer, anti-inflammatory and neuroprotective effects. Displays anticonvulsive activity via an increase in GABA levels and decreases Aβ production in animal models of Alzheimer's disease. Also attenuates NMDA-mediated excitation, blocks voltage-gated Na+ channels and modulates firing of neurons. Enables induction of pluripotent stem cells from somatic cells by Oct4 and Sox2. |
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