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Cat. Number
286269822106600
Chemical Name
Valproic acid, sodium salt
CAS Number
[1069-66-5]
Mol. Formula
C8H15NaO2
Mol. Weight
166.19
Qty 1
100mg
Synonym
Sodium 2-propylpentanoate
Solubility
Soluble to 100 mM in water
Storage condition
Desiccate at RT
References
Histone deacetylase inhibitor (IC50 = 400 μM) that exhibits anticancer, anti-inflammatory and neuroprotective effects. Displays anticonvulsive activity via an increase in GABA levels and decreases Aβ production in animal models of Alzheimer's disease. Also attenuates NMDA-mediated excitation, blocks voltage-gated Na+ channels and modulates firing of neurons. Enables induction of pluripotent stem cells from somatic cells by Oct4 and Sox2.
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