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| Cat. Number | 286251508657591 |
| Chemical Name | 17-AAG |
| CAS Number | [75747-14-7] |
| Mol. Formula | C31H43N3O8 |
| Mol. Weight | 585.7 |
| Qty 1 |
1mg |
| Synonym | 17-Demethoxy-17-(2-propenylamino)ge ldanamycin |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Desiccate at -20°C |
| References |
Inhibitor of heat shock protein 90 (Hsp90) chaperone activity, and an analog of geldanamycin (Cat. No. 1368). Subsequently inhibits the activity of oncogenic proteins such as p185erbB-2 (IC50 = 31 nM), N-ras, Ki-ras and c-Akt. Antitumor in vivo. |
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