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| Cat. Number | 285268869997461 |
| Chemical Name | BRL 54443 |
| Mol. Formula | C14H18N2O |
| Mol. Weight | 230.31 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 5-Hydroxy-3-(1-methylpiperidin-4-yl )-1H-indole |
| Solubility | Soluble to 50 mM in DMSO |
| Storage condition | Desiccate at +4°C |
| References | A potent 5-ht1E/1F receptor agonist (pEC50 values are 8.5 and 8.6 respectively). Displays > 30-fold selectivity over other 5-HT and dopamine receptors (pKi values are 8.7. 8.9, 7.2, 6.9, 7.2, 5.9, 7.0, 6.5, < 6, < 6, 6.3 and 6.2 for human 5-HT1E, 1F, 1A, 1B, 1D, 2A, 2B, 2C, 4, 7, D2 and D3 receptors respectively). Induces 5-HT2A receptor-mediated mouse aortic contraction in vitro (pEC50 = 6.52). Active in vivo. |
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