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| Cat. Number | 284717444545834 |
| Chemical Name | BI 78D3 |
| CAS Number | [883065-90-5] |
| Mol. Formula | C13H9N5O5S2 |
| Mol. Weight | 379.37 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 4-(2,3-Dihydro-1,4-benzodioxin-6-yl )-2,4-dihydro-5-[(5-nitro-2-thiazolyl)thio]-3H-1,2 ,4-triazol-3-one |
| Solubility | Soluble to 100 mM in DMSO and to 5 mM in ethanol |
| Storage condition | Store at +4°C |
| References | Competitive c-Jun N-terminal kinase (JNK) inhibitor (IC50 = 280 nM) that displays > 100 fold selectivity over p38α and no activity at mTOR and PI-3K. Inhibits JNK interacting protein 1 (JIP1)-JNK binding (IC50 = 500 nM) and prevents JNK substrate phosphorylation. Blocks JNK-dependent Con A-induced liver damage and restores insulin sensitivity in a mouse model of type II diabetes. Purity: >99 % |
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