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Cat. Number
284521167154066
Chemical Name
BAY-u 3405
CAS Number
[116649-85-5]
Mol. Formula
C21H21FN2O4S
Mol. Weight
416.47
Qty 1
10mg
Qty 2
50mg
Synonym
(3R)-3-[[(4-Fluorophenyl)sulfonyl]a mino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid
Solubility
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage condition
Desiccate at -20°C
References
Potent dual antagonist of TP/DP2 (CRTH2) prostanoid receptors (Ki values are 4.3, 4.5 and > 10000 nM for hDP2, hTP and hDP1 receptors respectively). Suppresses PGD2-induced migration of human eosinophils (IC50 = 170 nM).
Purity: >99 %
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