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Cat. Number
284392635169639
Chemical Name
BADGE
CAS Number
[1675-54-3]
Mol. Formula
C21H24O4
Mol. Weight
340.42
Qty 1
10mg
Qty 2
50mg
Synonym
2,2-Bis[4-(2,3-epoxypropoxy)phenyl] propane
Solubility
Soluble to 50 mM in ethanol and to 100 mM in DMSO
Storage condition
Desiccate at -20°C
References
PPARγ pure antagonist with micromolar affinity in 3T3-L1 and 3T3-F442A preadipocyte cells; selective over PPARδ and PPARα. Antagonizes the ability of rosiglitazone to stimulate transcriptional activity of PPARγ. Acts as a PPARγ agonist in an ECV304 cell line. Also produces PPARg-independent apoptosis of tumor cells via several mechanisms. Active in vivo.
Purity: >90 %
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