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| Cat. Number | 283852753340347 |
| Chemical Name | 环巴胺 Cyclopamine |
| CAS Number | [4449-51-8] |
| Mol. Formula | C27H41NO2 |
| Mol. Weight | 411.63 |
| Qty 1 |
1mg |
| Synonym | (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,1 1bR)-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b- Octadecahydro-3',6',10,11b-tetramethylspiro[9H-benzo [a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-3-ol |
| Solubility | Soluble to 5 mM in ethanol |
| Storage condition | Desiccate at -20°C |
| References |
Inhibitor of hedgehog (Hh) signaling, likely via direct inhibition of Smoothened, the accessory protein to the putative Hh receptor Patched. Anti-cancer and teratogenic in vivo. Depletes stem-like cancer cells in glioblastoma and blocks tumor engraftment. |
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