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Cat. Number
283476327354853
Chemical Name
Costunolide
CAS Number
[553-21-9]
Mol. Formula
C15H20O2
Mol. Weight
232.32
Qty 1
1mg
Qty 2
10mg
Synonym
(3aS,6E,10E,11aR)-3a,4,5,8,9,11a-He xahydro-6,10-dimethyl-3-methylene-cyclodeca[b]fura n-2(3H)-one
Solubility
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Storage condition
Store at -20°C
References
Inhibitor of human telomerase activity (IC50 = 65 μM in MCF-7 breast cancer cells). Suppresses proliferation and induces apoptosis in a variety of human tumor cell lines. Selectively blocks endothelial cell proliferation induced by VEGF. Inhibits expression of iNOS and IL-1β and disrupts NF-κB activation. Displays anti-inflammatory, antifungal and antiviral properties.
Purity: >97 %
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