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Cat. Number
283351651438284
Chemical Name
Compstatin
CAS Number
[206645-99-0]
Mol. Formula
C66H99N23O17S2
Mol. Weight
1550.77
Qty 1
1mg
Storage condition
Store at -20°C
References
Complement inhibitor; binds C3 inhibiting proteolytic cleavage by C3 convertase (IC50 = 28 μM) and activation of classical and alternative complement pathways (IC50 values are 63 and 12 μM respectively). Prolongs graft survival and reduces hyperacute rejection of ex vivo pig kidneys perfused with human blood and inhibits in vivo heparin/protamine-induced complement activation in baboons.
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