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Cat. Number
283304136989757
Chemical Name
COG 133
CAS Number
[514200-66-9]
Mol. Formula
C97H181N37O19
Mol. Weight
2169.73
Qty 1
1mg
Storage condition
Store at -20°C
References
Apolipoprotein (apoE) peptide fragment that functions via the low-density lipoprotein receptor-related protein (LRP). Substantially reduces the symptoms of experimental autoimmune encephalomyelitis, a model of human multiple sclerosis, and suppresses inflammation, demyelination and infiltration of cells into the spinal cord. Also acts as a non-competitive antagonist at α7 nicotinic acetylcholine receptors (IC50 = 445 nM).
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