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Cat. Number
282971560441004
Chemical Name
CI 966 hydrochloride
CAS Number
[110283-66-4]
Mol. Formula
C23H21F6NO3.HCl
Mol. Weight
509.87
Qty 1
10mg
Qty 2
50mg
Synonym
1-[2-[bis[4-(Trifluoromethyl)phenyl ]methoxy]ethyl]-1,2,5,6-tetrahydropyridine-3-carbo xylic acid hydrochloride
Solubility
Soluble to 10 mM in ethanol and to 100 mM in DMSO
Storage condition
Desiccate at RT
References
Selective inhibitor of the GABA transporter GAT-1 (IC50 values are 0.26 and 1.2 μM at cloned human and rat GAT-1 respectively). Displays over 200-fold selectivity over GAT-2 and GAT-3. Centrally active upon systemic administration in vivo. Anticonvulsive and neuroprotective.
Purity: >98 %
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