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| Cat. Number | 282742882020366 |
| Chemical Name | Chelerythrine chloride |
| CAS Number | [34316-15-9] |
| Mol. Formula | C21H18ClNO4 |
| Mol. Weight | 383.83 |
| Qty 1 |
5mg |
| Synonym | 1,2-Dimethoxy-12-methyl[1,3]benzodi oxolo[5,6-c]phenanthridinium chloride |
| Solubility | Soluble to 10 mM in water and to 10 mM in DMSO |
| Storage condition | Desiccate at -20°C |
| References | Potent, cell-permeable inhibitor of protein kinase C (IC50 = 660 nM); competitive with respect to the phosphate acceptor and non-competitive with respect to ATP. Has a wide range of biological activities, including antiplatelet, anti-inflammatory, antibacterial and antitumor effects. Activates MAPK pathways, independent of PKC inhibition. Inhibits binding of BclXL to Bak (IC50 = 1.5 μM) or Bad proteins and stimulates apoptosis. Purity: >98 % |
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