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/ Products Classification 点击展开+Cat. Number | 282728279551029 |
Chemical Name | Ch 55 |
CAS Number | [110368-33-7] |
Mol. Formula | C24H28O3 |
Mol. Weight | 364.47 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 4-[(1E)-3-[3,5-bis(1,1-Dimethylethy l)phenyl]-3-oxo-1-propenyl]benzoic acid |
Solubility | Soluble to 50 mM in ethanol and to 100 mM in DMSO |
Storage condition | Store at RT |
References | Highly potent synthetic retinoid that has high affinity for RAR-α and RAR-β receptors and low affinity for cellular retinoic acid binding protein (CRABP). Inhibits rabbit tracheal epithelial cell differentiation by inhibiting transglutaminase and increasing cholesterol sulfate (EC50 values are 0.02 and 0.03 nM respectively). Induces differentiation of embryonic carcinoma F9 and melanoma S91 cells (EC50 values are 0.26 and 0.5 nM respectively) and inhibits the induction of ornithine decarboxylase activity in 3T6 fibroblasts (EC50 = 1 nM). Purity: >98 % |