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| Cat. Number | 282352619788846 |
| Chemical Name | CCT 018159 |
| CAS Number | [171009-07-7] |
| Mol. Formula | C20H20N2O4 |
| Mol. Weight | 352.39 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 4-[4-(2,3-Dihydro-1,4-benzodioxin-6 -yl)-5-methyl-1H-pyrazol-3-yl]-6-ethyl-1,3-benzene diol |
| Solubility | Soluble to 5 mM in water and to 100 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Novel inhibitor of heat shock protein 90 (Hsp90) ATPase activity (IC50 = 5.7 μM) that displays selectivity over human Hsp72 and topoisomerase II. Inhibits proliferation of HCT116 human colon tumor cells and produces upregulation of Hsp70 and downregulation of c-Raf and cdk4. More soluble than 17-AAG (Cat. No. 1515) and is independent of NQO1/DT-diaphorase and P-glycoprotein expression. Purity: >98 % |
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