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/ Products Classification 点击展开+Cat. Number | 282335564013839 |
Chemical Name | CCMI |
CAS Number | [917837-54-8] |
Mol. Formula | C19H15Cl2N3O2 |
Mol. Weight | 388.25 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | [N-(4-Chlorophenyl)]-α-[(4-chlorophe nyl)-aminomethylene]-3-methyl-5-isoxazoleacetamide |
Solubility | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
Storage condition | Store at -20°C |
References | Positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors (nAChR). Evokes positive modulation of acetylcholine (ACh)-induced EC5 currents (EC50 = 0.7 μM). Exhibits cognitive-enhancing properties in rodent models; displays no cytotoxic effects in PC12 cells or rat primary cortical neurons. |
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