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Cat. Number
282335564013839
Chemical Name
CCMI
CAS Number
[917837-54-8]
Mol. Formula
C19H15Cl2N3O2
Mol. Weight
388.25
Qty 1
10mg
Qty 2
50mg
Synonym
[N-(4-Chlorophenyl)]-α-[(4-chlorophe nyl)-aminomethylene]-3-methyl-5-isoxazoleacetamide
Solubility
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Storage condition
Store at -20°C
References
Positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors (nAChR). Evokes positive modulation of acetylcholine (ACh)-induced EC5 currents (EC50 = 0.7 μM). Exhibits cognitive-enhancing properties in rodent models; displays no cytotoxic effects in PC12 cells or rat primary cortical neurons.
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