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/ Products Classification 点击展开+Cat. Number | 279357213124561 |
Chemical Name | DMH-1 |
CAS Number | [1206711-16-1] |
Mol. Formula | C24H20N4O |
Mol. Weight | 380.44 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 4-[6-[4-(1-Methylethoxy)phenyl]pyra zolo[1,5-a]pyrimidin-3-yl]-quinoline |
Solubility | Soluble to 50 mM in DMSO |
Storage condition | Store at +4°C |
References | Selective inhibitor of the bone morphogenic protein (BMP) ALK2 receptor (IC50 = 108 nM). Exhibits no detectable inhibition of AMPK, ALK5, KDR (VEGFR-2) or PDGFRβ receptors. Blocks BMP4-induced phosphorylation of Smads 1, 5 and 8 in HEK293 cells. Purity: >98 % |
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