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Cat. Number
279357213124561
Chemical Name
DMH-1
CAS Number
[1206711-16-1]
Mol. Formula
C24H20N4O
Mol. Weight
380.44
Qty 1
10mg
Qty 2
50mg
Synonym
4-[6-[4-(1-Methylethoxy)phenyl]pyra zolo[1,5-a]pyrimidin-3-yl]-quinoline
Solubility
Soluble to 50 mM in DMSO
Storage condition
Store at +4°C
References
Selective inhibitor of the bone morphogenic protein (BMP) ALK2 receptor (IC50 = 108 nM). Exhibits no detectable inhibition of AMPK, ALK5, KDR (VEGFR-2) or PDGFRβ receptors. Blocks BMP4-induced phosphorylation of Smads 1, 5 and 8 in HEK293 cells.
Purity: >98 %
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