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/ Products Classification 点击展开+Cat. Number | 278981510750519 |
Chemical Name | Demethylasterriquinone B1 |
CAS Number | [78860-34-1] |
Mol. Formula | C32H30N2O4 |
Mol. Weight | 506.59 |
Qty 1 |
5mg |
Synonym | 2-[2-(1,1-Dimethyl-2-propenyl)-1H-i ndol-3-yl]-3,6-dihydroxy-5-[7-(3-methyl-2-butenyl) -1H-indol-3-yl]-2,5-cyclohexadiene-1,4-dione |
Solubility | Soluble to 100 mM in DMSO |
Storage condition | Desiccate at -20°C |
References | Selective insulin receptor (IR) activator/mimetic (EC50 values are 3 - 6 μM for IRTK and 100 μM for IGF1R and EGFR). Increases IR β subunit tyrosine phosphorylation and downstream activation of PI 3-kinase and Akt, but not ERK. Induces glucose uptake in adipocytes and skeletal muscle in vitro, without enhancing vascular proliferation. Binds GAPDH. Purity: >98 % |