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Cat. Number
278972354411956
Chemical Name
Deguelin
CAS Number
[522-17-8]
Mol. Formula
C23H22O6
Mol. Weight
394.42
Qty 1
10mg
Synonym
(7aS,13aS)-13,13a-Dihydro-9,10-dime thoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6',5'- e]pyran-7(7aH)-one
Solubility
Soluble to 50 mM in ethanol and to 100 mM in DMSO
Storage condition
Store at +4°C
References
Anticancer and antiviral agent; chemopreventive and pro-apoptotic. Inhibits phorbol ester-induced ornithine decarboxylase and NADH:ubiquinone oxidoreductase activities (IC50 values are 11 and 6.9 nM respectively). Inhibits PI 3-kinase and reduces pAkt levels in pre-malignant and malignant human bronchial epithelial cells. Active in vivo.
Purity: >98 %
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