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| Cat. Number | EO 1428 |
| Chemical Name | EO 1428 |
| CAS Number | [321351-00-2] |
| Mol. Formula | C20H16BrClN2O |
| Mol. Weight | 415.71 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | (2-Methylphenyl)-[4-[(2-amino-4-bro mophenyl)amino]-2-chlorophenyl]methanone |
| Solubility | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| Storage condition | Store at +4°C |
| References | Selective inhibitor of p38α and p38β2 that displays no activity at p38γ, p38δ, ERK1/2 and JNK1. Inhibits production of inflammatory cytokines including IL-8, TNF-α, IL-6, IL-1β and IL-10 (IC50 values are 4, 5, 17, 30 and 74 nM respectively). Displays anti-inflammatory activity in murine models of acute and chronic dermatitis. Purity: >98 % |
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