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Cat. Number
EMD 66684
Chemical Name
EMD 66684
CAS Number
[187683-79-0]
Mol. Formula
C28H30N8O2.HCl
Mol. Weight
547.05
Qty 1
10mg
Qty 2
50mg
Synonym
2-Butyl-3,4-dihydro-N,N-dimethyl-4- oxo-3-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl-4-yl]met hyl]-5H-imidazo[4,5-c]pyridine-5-acetamide hydrochloride
Solubility
Soluble to 50 mM in DMSO and to 50 mM in ethanol
Storage condition
Desiccate at +4°C
References
Highly potent and very selective non-peptide angiotensin AT1 receptor antagonist (IC50 values are 0.7 and > 10000 nM for AT1 and AT2 receptors respectively). Potently inhibits angiotensin II-induced contractions in isolated rabbit aorta (IC50 = 0.2 nM) and reduces blood pressure in hypertensive rats.
Purity: >98 %
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