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Cat. Number
Efonidipine hydrochloride monoethanolate
Chemical Name
Efonidipine hydrochloride monoethanolate
CAS Number
[111011-76-8]
Mol. Formula
C34H38N3O7P.HCl.C2H5OH
Mol. Weight
714.18
Qty 1
10mg
Qty 2
50mg
Synonym
5-(5,5-Dimethyl-2-oxido-1,3,2-dioxa phosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-n itrophenyl)-3-pyridinecarboxylic acid 2-[phenyl(phenylmethyl)amino]ethyl ester hydrochloride monoethanolate
Solubility
Soluble to 100 mM in DMSO
Storage condition
Desiccate at +4°C
References
Selective blocker of L-type and T-type Ca2+ channels. Displays minimal inhibition of N- and P/Q-type channels and no inhibition of R-type channels. R(-) and S(+)-enantiomers displays different channel selectivity; S(+)-Efonidipine blocks L-type and T-type channels whereas R(-)-Efonidipine displays selectivity for T-type channels. Exhibits antihypertensive activity.
Purity: >99 %
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