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Cat. Number
Edelfosine
Chemical Name
Edelfosine
CAS Number
[77286-66-9]
Mol. Formula
C27H58NO6P
Mol. Weight
523.73
Qty 1
10mg
Synonym
(7R)-4-Hydroxy-7-methoxy-N,N,N-trim ethyl-3,5,9-trioxa-4-phosphaheptacosan-1-aminium-4 -oxide
Solubility
Soluble to 25 mM in water and to 100 mM in ethanol
Storage condition
Store at -20°C
References
Synthetic lysophospholipid analog that selectively inhibits phosphatidylinositol phospholipase C (IC50= 9.6 μM in fibroblasts and adenocarcinoma cells). Also acts as an agonist at platelet-activating factor (PAF) receptors. Antitumor lipid; selectively induces apoptosis in tumor cells, sparing normal cells.
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