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Cat. Number
Fumagillin
Chemical Name
Fumagillin
CAS Number
[23110-15-8]
Mol. Formula
C26H34O7
Mol. Weight
458.55
Qty 1
1mg
Synonym
(2E,4E,6E,8E)-Mono[(3R,4S,5S,6R)-5- methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-butenyl) oxiranyl]-1-oxaspiro[2.5]oct-6-yl] 2,4,6,8-decatetraenedioic acid ester
Solubility
Soluble to 3 mM in ethanol
Storage condition
Store at -20°C
References
Antibiotic and antiangiogenic agent; covalently binds and inhibits methionine aminopeptidase-2. Inhibits endothelial cell proliferation in vitro and tumor-induced angiogenesis in vivo. Also inhibits tumor growth in mice. Analog available, TNP 470 (Cat.No. 3750).
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