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| Cat. Number | Fluticasone propionate |
| Chemical Name | Fluticasone propionate |
| CAS Number | [80474-14-2] |
| Mol. Formula | C25H31F3O5S |
| Mol. Weight | 500.57 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | (6α,11β,16α,17α)-6,9-Difluoro-11-hydrox y-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-di ene-17-carbothioic acid fluoromethyl ester |
| Solubility | Soluble to 50 mM in DMSO |
| Storage condition | Store at RT |
| References | High affinity, selective glucocorticoid receptor agonist (Kd = 0.5 nM). Potently stimulates glucocorticoid receptor-mediated transactivation of gene expression and enhances human eosinophil apoptosis (EC50 = 3.7 nM) in vitro. Inhibits mast cell accumulation in nasal mucosa following topical administration. Lipophilic, clinically-used anti-inflammatory agent with low oral bioavailability. |
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