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Cat. Number
GYKI 52466 dihydrochloride
Chemical Name
GYKI 52466 dihydrochloride
CAS Number
[102771-26-6]
Mol. Formula
C17H15N3O2.2HCl
Mol. Weight
366.24
Qty 1
10mg
Qty 2
50mg
Synonym
4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2 ,3]benzodiazepin-5-yl)-benzenamine dihydrochloride
Solubility
Soluble to 50 mM in DMSO and to 10 mM in water
Storage condition
Desiccate at RT
References
Selective non-competitive AMPA receptor antagonist (IC50 values are 10-20, ~ 450 and >> 50 μM for AMPA- , kainate- and NMDA-induced responses respectively). Skeletal muscle relaxant and orally-active anticonvulsant. Has anti-proliferative effects in transformed cells. Also available as part of the AMPA Receptor Tocriset™. Also available as part of the Kainate Receptor Tocriset™.
Purity: >99 %
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