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/ Products Classification 点击展开+Cat. Number | GYKI 52466 dihydrochloride |
Chemical Name | GYKI 52466 dihydrochloride |
CAS Number | [102771-26-6] |
Mol. Formula | C17H15N3O2.2HCl |
Mol. Weight | 366.24 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2 ,3]benzodiazepin-5-yl)-benzenamine dihydrochloride |
Solubility | Soluble to 50 mM in DMSO and to 10 mM in water |
Storage condition | Desiccate at RT |
References | Selective non-competitive AMPA receptor antagonist (IC50 values are 10-20, ~ 450 and >> 50 μM for AMPA- , kainate- and NMDA-induced responses respectively). Skeletal muscle relaxant and orally-active anticonvulsant. Has anti-proliferative effects in transformed cells. Also available as part of the AMPA Receptor Tocriset™. Also available as part of the Kainate Receptor Tocriset™. Purity: >99 % |