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| Cat. Number | GW 0742 |
| Chemical Name | GW 0742 |
| CAS Number | [317318-84-6] |
| Mol. Formula | C21H17F4NO3S2 |
| Mol. Weight | 471.49 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | [4-[[[2-[3-Fluoro-4-(trifluoromethy l)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-meth ylphenoxy]acetic acid |
| Solubility | Soluble to 50 mM in ethanol and to 100 mM in DMSO |
| Storage condition | Desiccate at +4°C |
| References | Potent and highly selective PPARδ agonist. EC50 values are 0.001, 1.1 and 2 μM for transactivation of human PPARδ, -α, and -γ receptors respectively. Neuroprotective in rat cerebellar granule neuronal cultures after brief (12-hour) exposure but exhibits inherent toxicity after prolonged (48-hour) incubation. Increases rate of fatty acid oxidation and protects against ischemia/reperfusion injury in neonatal and adult cardiomyocytes. Purity: >98 % |
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