服务热线
021-60498804
| Cat. Number | GSK 429286 |
| Chemical Name | GSK 429286 |
| Mol. Formula | C21H16F4N4O2 |
| Mol. Weight | 432.37 |
| Qty 1 |
1mg |
| Qty 2 | 50mg |
| Synonym | 4-[4-(Trifluoromethyl)phenyl]-N-(6- Fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-1,4,5,6-tet rahydro-3-pyridinecarboxamide |
| Solubility | Soluble to 100 mM in DMSO and to 25 mM in ethanol |
| Storage condition | Store at +4°C |
| References | Selective Rho-kinase inhibitor (IC50 values are 14, 780 and 1940 nM for ROCK1, RSK and p70S6K respectively). Reverses adrenalin-induced contraction of the rat aortic ring (IC50 = 190 nM) and causes a dose-dependent decrease in mean arterial blood pressure in spontaneous hypertensive rats. Orally active. Purity: >97 % |
Copyright © 2022 上海惠诚生物科技有限公司
沪ICP备2021037845号-6
