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Cat. Number
LY 341495
Chemical Name
LY 341495
CAS Number
[201943-63-7]
Mol. Formula
C20H19NO5
Mol. Weight
353.37
Qty 1
1mg
Qty 2
50mg
Synonym
(2S)-2-Amino-2-[(1S,2S)-2-carboxycy cloprop-1-yl]-3-(xanth-9-yl) propanoic acid
Solubility
Soluble to 10 mM in DMSO and to 100 mM in 1.2eq. NaOH
Storage condition
Store at RT
References

Highly potent and selective group II metabotropic glutamate receptor antagonist (Ki/IC50 values are 2.3, 1.3, 173, 990, 6800, 8200 and 22000 nM for human mGlu2, mGlu3, mGlu8 , mGlu7a, mGlu1a, mGlu5a and mGlu4a receptors respectively). Readily brain penetrant and active in vivo. Also available as part of the Group II mGlu Receptor Tocriset™, Group III mGlu Receptor Tocriset™ and Mixed mGlu Receptor Tocriset™.
Purity: >98 %

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