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/ Products Classification 点击展开+Cat. Number | GIT 27 |
Chemical Name | GIT 27 |
CAS Number | [6501-72-0] |
Mol. Formula | C11H11NO3 |
Mol. Weight | 205.21 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 4,5-Dihydro-3-phenyl-5-isoxazoleace tic acid |
Solubility | Soluble to 100 mM in DMSO |
Storage condition | Store at +4°C |
References | Orally active immunomodulatory agent that primarily targets macrophages. Inhibits TNF-α secretion via interference of macrophage toll-like receptor (TLR) 4 and TLR 2/6 signaling pathway. Also reduces the secretion of pro-inflammatory cytokines IL1-β, IL-10 and IFN-γ. Antidiabetogenic; prevents IL-β and IFN-γ-induced pancreatic islet cell death in vitro. Purity: >99 % |