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| Cat. Number | Gemcitabine hydrochloride |
| Chemical Name | Gemcitabine hydrochloride |
| CAS Number | [122111-03-9] |
| Mol. Formula | C9H11F2N3O4.HCl |
| Mol. Weight | 299.66 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | (+)-2'-Deoxy-2',2'-difluorocytidine hydrochloride |
| Solubility | Soluble to 100 mM in water and to 50 mM in DMSO |
| Storage condition | Desiccate at +4°C |
| References | Deoxycytidine analog that inhibits DNA synthesis. Metabolized to form gemcitabine triphosphate (dFdCTP) and gemcitabine diphosphate (dFdCDP). dFdCTD inhibits ribonucleotide reductase causing a reduction in cellular nucleotides. dFdCTP is incorporated in DNA resulting in DNA strand termination. Displays antitumor activity in vitro and in vivo. Purity: >99 % |
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