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/ Products Classification 点击展开+Cat. Number | Gedunin |
Chemical Name | Gedunin |
CAS Number | [2753-30-2] |
Mol. Formula | C28H34O7 |
Mol. Weight | 482.57 |
Qty 1 |
10mg |
Synonym | (1S,3aS,4aR,4bS,5R,6aR,10aR,10bR,12 aS)-5-(Acetyloxy)-1-(3-furanyl)-1,5,6,6a,7,10a,10b ,11,12,12a,decahydro-4b,7,7,10a,12a,-pentamethylox ireno[c]phenanthro[1,2-d]pyran-3,8(3aH,4bH)-dione |
Solubility | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
Storage condition | Store at +4°C |
References | Naturally occurring Hsp90 inhibitor. Induces Hsp90-dependent client protein degradation and displays antiproliferative activity in vitro (IC50 values are 3.22, 8.84 and 16.8 μM in SKBr3, MCF-7 and CaCo-2 cancer cell lines respectively). Also exhibits antimalarial activity against P. falciparum (IC50 values are 0.14 and 3.1 μM in parasite development and [3H]-hypoxanthine uptake assays respectively). Purity: >98 % |