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Cat. Number
Thioperamide
Chemical Name
Thioperamide
CAS Number
[106243-16-7]
Mol. Formula
C15H24N4S
Mol. Weight
292.44
Qty 1
10mg
Qty 2
50mg
Synonym
N-Cyclohexyl-4-(imidazol-4-yl)-1-pi peridinecarbothioamide
Solubility
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage condition
Store at -20°C
References
Potent histamine H3 and H4 antagonist/inverse agonist. Ki values are 25 and 27 nM for human recombinant H3 and H4 receptors respectively. Blocks eosinophil shape change (IC50 = 1.4 μM) and chemotaxis (IC50 = 519 nM) induced by histamine. Freely crosses the blood-brain barrier. Also available as part of the Histamine H3 Receptor Tocriset™.
Purity: >99 %
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