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Cat. Number
Hispidulin
Chemical Name
Hispidulin
CAS Number
[1447-88-7]
Mol. Formula
C16H12O6
Mol. Weight
300.27
Qty 1
10mg
Synonym
5,7-Dihydroxy-2-(4-hydroxyphenyl)-6 -methoxy-4H-1-benzopyran-4-one
Solubility
Soluble to 25 mM in DMSO and to 10 mM in ethanol
Storage condition
Desiccate at -20°C
References
Partial positive allosteric modulator at the benzodiazepine receptor (IC50 = 1.3 μM for inhibition of flumazenil binding); natural sage flavone. Stimulates GABA-induced chloride currents in Xenopus oocytes expressing α1-, α2-, α3-, α5- or α6-β2 γ2S GABAA receptors. Brain penetrant; oral administration reduces seizures in a gerbil model of epilepsy. Also has antifungal, antiproliferative, antioxidant and antithrombotic properties.
Purity: >98 %
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