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| Cat. Number | (±)-HIP-B |
| Chemical Name | (±)-HIP-B |
| CAS Number | [227619-65-0] |
| Mol. Formula | C6H8N2O4 |
| Mol. Weight | 172.14 |
| Qty 1 |
10mg |
| Synonym | (±)-3-Hydroxy-4,5,6,6a-tetrahydro-3a H-pyrrolo[3,4-d]isoxazole-6-carboxylic acid |
| Solubility | Soluble to 20 mM in water |
| Storage condition | Store at +4°C |
| References | Potent, non-competitive excitatory amino acid transporter (EAAT) blocker. Preferentially inhibits glutamate-induced [3H]D-aspartate release (IC50 = 1.2 μM) rather than [3H]L-glutamate uptake (IC50 = 16.9 μM). Moderately selective; displays no affinity for NMDA and metabotropic glutamate receptors, and low affinity for AMPA and kainate receptors (IC50 values are 35 and 45 μM respectively). Purity: >98 % |
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