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| Cat. Number | H 1152 dihydrochloride |
| Chemical Name | H 1152 dihydrochloride |
| CAS Number | [451462-58-1] |
| Mol. Formula | C16H21N3O2S.2HCl |
| Mol. Weight | 392.34 |
| Qty 1 |
1mg |
| Synonym | (S)-(+)-2-Methyl-1-[(4-methyl-5-iso quinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride |
| Solubility | Soluble to 100 mM in water and to 50 mM in DMSO |
| Storage condition | Desiccate at +4°C |
| References | Rho-kinase (ROCK) inhibitor that displays high selectivity over other protein kinases (IC50 values are 0.012, 0.180, 0.360, 0.745, 3.03, 5.68 and 28.3 μM for ROCKII, CAMKII, PKG, Aurora A, PKA, PKC and MLCK respectively). Inhibits sulprostone-induced contractions in guinea pig aorta (IC50 = 190 nM) and displays proerectile effects in rats. Purity: >98 % |
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