服务热线
021-60498804
| Cat. Number | I9060 |
| Chemical Name | I9060 IWP-2 686770-61-6 |
| CAS Number | 686770-61-6 |
| Mol. Formula | C22H18N4O2S3 |
| Mol. Weight | 466.6 |
| Qty 1 |
1mg |
| Qty 2 | 5mg |
| Appearance | White to off white powder |
| Application Notes | ≥98% |
| Synonym | IWP2 |
| Solubility | DMF 22 mg/mL warmed (47.14 mM) DMSO 4 mg/mL warmed (8.57 mM) Water Insoluble |
| Storage condition | -20°C |
| References | IWP-2 is an inhibitor of PORCN that inhibits Wnt signaling, exhibiting anticancer activity. IWP-2 increases activity of caspases 3 and 7, inhibiting proliferation, migration, and invasion of gastric cancer cells and colorectal cancer cells. References Frewer KA, Sanders AJ, Owen S, et al. A role for WISP2 in colorectal cancer cell invasion and motility. Cancer Genomics Proteomics. 2013 Jul-Aug;10(4):187-96. PMID: 23893926. Mo ML, Li MR, Chen Z, et al. Inhibition of the Wnt palmitoyltransferase porcupine suppresses cell growth and downregulates the Wnt/β-catenin pathway in gastric cancer. Oncol Lett. 2013 May;5(5):1719-1723. PMID: 23761839. 上海惠诚生物科技有限公司自2010年成立以来，一直致力于为客户提供试剂，仪器设备和耗材一站式服务。目前在苏州和南通的研发生产基地，专注于体外诊断蛋白，靶标蛋白，工业用酶和细胞因子的生产和定制，按照GMP标准，为工业客户提供大包装蛋白原料。
更多产品请联系惠诚生物！ 蛋白原料网站：www.acediag.com 全国统一服务热线：021- 60496554 24小时手机服务: 13917250134（同微信）QQ：1715451510 Email：info@e-biochem.com |
Copyright © 2022 上海惠诚生物科技有限公司
沪ICP备2021037845号-6
