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/ Products Classification 点击展开+Cat. Number | IRL-2500 |
Chemical Name | IRL-2500 |
CAS Number | [169545-27-1] |
Mol. Formula | C36H35N3O4 |
Mol. Weight | 573.69 |
Qty 1 |
10mg |
Synonym | N-3-[1,1'-Biphenyl]-4-yl-N-(3,5-dime thylbenzoyl)-N-methyl-D-alanyl-L-tryptophan |
Solubility | Soluble to 100 mM in 1eq. NaOH |
Storage condition | Desiccate at RT |
References | Potent endothelin receptor antagonist; shows some selectivity for ETB receptors (IC50 values are 1.3 and 94 nM for ETB and ETA receptors respectively). Inhibits ETB receptor-mediated blood pressure increase and renal vascular resistance in rats in vivo. Purity: >99 % |
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