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Cat. Number
IRL-2500
Chemical Name
IRL-2500
CAS Number
[169545-27-1]
Mol. Formula
C36H35N3O4
Mol. Weight
573.69
Qty 1
10mg
Synonym
N-3-[1,1'-Biphenyl]-4-yl-N-(3,5-dime thylbenzoyl)-N-methyl-D-alanyl-L-tryptophan
Solubility
Soluble to 100 mM in 1eq. NaOH
Storage condition
Desiccate at RT
References
Potent endothelin receptor antagonist; shows some selectivity for ETB receptors (IC50 values are 1.3 and 94 nM for ETB and ETA receptors respectively). Inhibits ETB receptor-mediated blood pressure increase and renal vascular resistance in rats in vivo.
Purity: >99 %
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