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| Cat. Number | Iressa |
| Chemical Name | Iressa |
| CAS Number | [184475-35-2] |
| Mol. Formula | C22H24ClFN4O3 |
| Mol. Weight | 446.9 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N-(3-chloro-4-fluoro-phenyl)-7-meth oxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine |
| Solubility | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
| Storage condition | Store at RT |
| References | Orally active, selective inhibitor of EGFR tyrosine kinase (IC50 = 23 - 79 nM). Shows minimal activity against ErbB2, KDR, c-flt, PKC, MEK and ERK-2. Blocks EGFR autophosphorylation and inhibits tumor growth in mice bearing a range of human xenografts. Purity: >98 % |
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