服务热线
021-60498804
产品中心
/ Products Classification 点击展开+Cat. Number | 5-Iodo-A-85380 dihydrochloride |
Chemical Name | 5-Iodo-A-85380 dihydrochloride |
CAS Number | [213764-92-2] |
Mol. Formula | C9H11IN2O.2HCl |
Mol. Weight | 363.03 |
Qty 1 |
10mg |
Synonym | 3-[(2S)-2-Azetidinylmethoxy]-5-iodo pyridine dihydrochloride |
Solubility | Soluble to 100 mM in water and to 100 mM in DMSO |
Storage condition | Desiccate at +4°C |
References | A highly potent and subtype-selective agonist for the α4β2 and α6β2 nicotinic acetylcholine receptors. Activates α-CTx-MII-sensitive and -insensitive components of [3H]dopamine release from rat striatal synaptosomes, corresponding to α6β2 and α4β2 (EC50 values are 12.7 and ~35 nM respectively). ~5000- , 25000- and 140000-fold selective over α3β4, α7 and muscle nAChR receptors respectively. Precursor (Cat. No. 1527) also available. Purity: >99 % |