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Cat. Number
5-Iodo-A-85380 dihydrochloride
Chemical Name
5-Iodo-A-85380 dihydrochloride
CAS Number
[213764-92-2]
Mol. Formula
C9H11IN2O.2HCl
Mol. Weight
363.03
Qty 1
10mg
Synonym
3-[(2S)-2-Azetidinylmethoxy]-5-iodo pyridine dihydrochloride
Solubility
Soluble to 100 mM in water and to 100 mM in DMSO
Storage condition
Desiccate at +4°C
References
A highly potent and subtype-selective agonist for the α4β2 and α6β2 nicotinic acetylcholine receptors. Activates α-CTx-MII-sensitive and -insensitive components of [3H]dopamine release from rat striatal synaptosomes, corresponding to α6β2 and α4β2 (EC50 values are 12.7 and ~35 nM respectively). ~5000- , 25000- and 140000-fold selective over α3β4, α7 and muscle nAChR receptors respectively. Precursor (Cat. No. 1527) also available.
Purity: >99 %
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