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| Cat. Number | Indirubin-3'-oxime |
| Chemical Name | Indirubin-3'-oxime |
| CAS Number | [160807-49-8] |
| Mol. Formula | C16H11N3O2 |
| Mol. Weight | 277.28 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 3-[1,3-Dihydro-3-(hydroxyimino)-2H- indol-2-ylidene]-1,3-dihydro-2H-indol-2-one |
| Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| Storage condition | Store at RT |
| References | Protein kinase inhibitor; inhibits cyclin-dependent kinases (IC50 = 0.18 - 3.33 μM) and GSK-3β (IC50 = 0.19 μM). Inhibits CDK5- and GSK-3β-mediated tau phosphorylation, a process over-active in Alzheimer disease states. Also inhibits AMPK, LCK and SGK. Induces cell cycle arrest and inhibits cell proliferation. Purity: >99 % |
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