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Cat. Number
Indiplon
Chemical Name
Indiplon
CAS Number
[325715-02-4]
Mol. Formula
C20H16N4O2S
Mol. Weight
376.43
Qty 1
10mg
Qty 2
50mg
Synonym
N-Methyl-N-[3-[3-[2-thienylcarbonyl ]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]acetamide
Solubility
Soluble to 50 mM in DMSO
Storage condition
Store at +4°C
References
Potent GABAA receptor positive allosteric modulator that acts at the benzodiazepine site (Ki values are 1.2 and 1.7 nM in rat frontal cortex and cerebellum respectively). Displays ~ 10-fold selectivity for α1 subunit-containing receptors (EC50 values are 2.6, 24, 60 and 77 nM for α1β2γ2, α2β2γ2, α3β3γ2 and α5β2γ2 receptors respectively). Exhibits sedative, hypnotic, anxiolytic and anticonvulsant activity in vivo and is orally active.
Purity: >99 %
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