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| Cat. Number | JZL 184 |
| Chemical Name | JZL 184 |
| CAS Number | [1101854-58-3] |
| Mol. Formula | C27H24N2O9 |
| Mol. Weight | 520.49 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 4-[Bis(1,3-benzodioxol-5-yl)hydroxy methyl]-1-piperidinecarboxylic acid 4-nitrophenyl ester |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Store at -20°C |
| References | Potent and selective monoacylglycerol lipase (MAGL) inhibitor. Blocks hydrolysis of the endocannabinoid 2-arachidonyl glycerol (2-AG) in vivo in the mouse brain (IC50 = 8 nM). Potentiates depolarization-induced suppression of excitability in cerebellar Purkinje neurons. Exhibits >300-fold selectivity for MAGL over FAAH in vitro. Purity: >98 % |
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