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/ Products Classification 点击展开+Cat. Number | JP 1302 dihydrochloride |
Chemical Name | JP 1302 dihydrochloride |
CAS Number | [80259-18-3] |
Mol. Formula | C24H24N4.2HCl |
Mol. Weight | 441.4 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | N-[4-(4-Methyl-1-piperazinyl)phenyl ]-9-acridinamine dihydrochloride |
Solubility | Soluble to 100 mM in water and to 5 mM in DMSO |
Storage condition | Desiccate at -20°C |
References | α2C-adrenoceptor antagonist that displays ~ 50-fold selectivity over other α2-adrenoceptor subtypes (Ki values are 28, 1470, 1700 and 3150 nM for human α2C, α2B, α2D and α2A subtypes respectively). Potently antagonizes adrenalin-stimulated 35GTPγS binding in vitro (KB = 16 nM) and produces antidepressant and antipsychotic-like effects in vivo. Purity: >99 % |
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