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Cat. Number
JP 1302 dihydrochloride
Chemical Name
JP 1302 dihydrochloride
CAS Number
[80259-18-3]
Mol. Formula
C24H24N4.2HCl
Mol. Weight
441.4
Qty 1
10mg
Qty 2
50mg
Synonym
N-[4-(4-Methyl-1-piperazinyl)phenyl ]-9-acridinamine dihydrochloride
Solubility
Soluble to 100 mM in water and to 5 mM in DMSO
Storage condition
Desiccate at -20°C
References
α2C-adrenoceptor antagonist that displays ~ 50-fold selectivity over other α2-adrenoceptor subtypes (Ki values are 28, 1470, 1700 and 3150 nM for human α2C, α2B, α2D and α2A subtypes respectively). Potently antagonizes adrenalin-stimulated 35GTPγS binding in vitro (KB = 16 nM) and produces antidepressant and antipsychotic-like effects in vivo.
Purity: >99 %
下一个:JTC 801上一个:JNJ 7777120
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