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Cat. Number
JNJ 303
Chemical Name
JNJ 303
CAS Number
[878489-28-2]
Mol. Formula
C21H29ClN2O4S
Mol. Weight
440.98
Qty 1
10mg
Qty 2
50mg
Synonym
2-(4-Chlorophenoxy)-2-methyl-N-[5-[ (methylsulfonyl)amino]tricyclo[3.3.1.13,7]dec-2-yl ]-propanamide
Solubility
Soluble to 25 mM in DMSO
Storage condition
Store at +4°C
References
Potent IKs blocker (IC50 = 64 nM). Displays no effects on other cardiac channels; IC50 values are 3.3, >10, 11.1 and 12.6 μM for INa, ICa, Ito and IKr channels respectively. Prolongs QT and causes unprovoked torsades de pointes (TdP).
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