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/ Products Classification 点击展开+Cat. Number | JNJ 303 |
Chemical Name | JNJ 303 |
CAS Number | [878489-28-2] |
Mol. Formula | C21H29ClN2O4S |
Mol. Weight | 440.98 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 2-(4-Chlorophenoxy)-2-methyl-N-[5-[ (methylsulfonyl)amino]tricyclo[3.3.1.13,7]dec-2-yl ]-propanamide |
Solubility | Soluble to 25 mM in DMSO |
Storage condition | Store at +4°C |
References | Potent IKs blocker (IC50 = 64 nM). Displays no effects on other cardiac channels; IC50 values are 3.3, >10, 11.1 and 12.6 μM for INa, ICa, Ito and IKr channels respectively. Prolongs QT and causes unprovoked torsades de pointes (TdP). |