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/ Products Classification 点击展开+Cat. Number | JNJ 17203212 |
Chemical Name | JNJ 17203212 |
CAS Number | [821768-06-3] |
Mol. Formula | C17H15F6N5O |
Mol. Weight | 419.32 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 4-[3-(Trifluoromethyl)-2-pyridinyl] -N-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazinec arboxamide |
Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
Storage condition | Store at +4°C |
References | Reversible, competitive and potent TRPV1 antagonist (pKi values are 6.5, 7.1 and 7.3 at rat, guinea pig and human TRPV1 respectively). Inhibits capsaicin- and H+-induced channel activation (pIC50 values are 6.32 and 7.23 respectively) and exhibits antitussive and analgesic activity in vivo. Purity: >99 % |