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Cat. Number
JNJ 17203212
Chemical Name
JNJ 17203212
CAS Number
[821768-06-3]
Mol. Formula
C17H15F6N5O
Mol. Weight
419.32
Qty 1
10mg
Qty 2
50mg
Synonym
4-[3-(Trifluoromethyl)-2-pyridinyl] -N-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazinec arboxamide
Solubility
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage condition
Store at +4°C
References
Reversible, competitive and potent TRPV1 antagonist (pKi values are 6.5, 7.1 and 7.3 at rat, guinea pig and human TRPV1 respectively). Inhibits capsaicin- and H+-induced channel activation (pIC50 values are 6.32 and 7.23 respectively) and exhibits antitussive and analgesic activity in vivo.
Purity: >99 %
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